Market share of top 20 companies for orphan drugs worldwide 2017 and 2024

The data shows the top 20 global pharmaceutical companies based on revenue market share generated by orphan drugs in 2024 compared to their share in 2017. In 2017, Roche's orphan drugs market share accounted for 8.2% of the world's market and is expected to decrease down to 5.2% by 2024. Orphan drugs are used to target rare diseases or disorders, which in the U.S. is defined as less than 200,000 patients. The development of orphan drugs are currently incentivized in the U.S. through the Orphan Drug Act of 1983.