The data illustrates a list of selected FDA-approved prescription drugs, which were later pulled from the United States market. The longest running FDA-approved drug which was later recalled from the market was Darvon & Darvocet, between 1955 and 2010, which stayed in the market for 55 years. The reason for the recall was serious toxicity to the heart: between 1981 and 1999 there were over 2,110 deaths reported connected to that drug. According to the Food and Drug Adminitration (FDA), a "drug is removed from the market when its risks outweigh its benefits.
Accutane, isotretinoin (1982-2009) | 27 |
Baycol, cerivastatin (1998-2001) | 3 |
Bextra, valdecoxib (2001-2005) | 3.3 |
Cylert, pemoline (1975-2010) | 30 |
Darvon & Darvocet, propoxyphene (1955-2010) | 55 |
DBI, phenformin (1959-1978) | 19 |
DES, diethylstibestrol (1940-1971) | 31 |
Duract, bromfenac (1997-1998) | 1 |
Ergamisol, levamisole (1989-2000) | 11 |
Hismanal, astemizole (1988-1999) | 11 |
Lotronex, astemizole (2000) | 0.8 |
Meridia, sibutramine (1997-2010) | 13 |
Merital & Alival, nomifensine (1982-1985) | 3 |
Micturin, terodiline (1989-1991) | 2 |
Mylotarg, gemtuzumab ozogamicin (2000-2010) | 10 |
Omniflox, temafloxacin (1992) | 0.3 |
Palladone, hydromorphone hydrochloride, extended-release (2005) | 0.5 |
Permax, pergolide (1988-2007) | 19 |
Pondimin, fenfluramine (1973-1997) | 24 |
Posicor, mibefradil (1997-1998) | 1 |
Propulsid, cisapride (1993-2000) | 7 |
PTZ & Metrazol, pentylenetetrazol (1934-1982) | 48 |
Quaaluude, methaqualone (1962-1985) | 23 |
Raplon, rapacuronium (1999-2001) | 2 |
Raptiva, efalizumab (2003-2009) | 6 |
Raxar, grepafloxacin (1997-1999) | 2 |
Redux, dexfenfluramine (1996-1997) | 1 |
Rezulin, troglitazone (1997-2000) | 3.25 |
Selacryn, tienilic acid (1979-1982) | 3 |
Seldane, terfenadine (1985-1998) | 13 |
Trasylol, aprotinin (1993-2008) | 15 |
Vioxx, rofecoxib (1999-2004) | 5.3 |
Xigris, drotrecogin alfa (2001-2011) | 10 |
Zelmid, zimelidine (1982) | 0 |
Zelnorm, tegaserod maleate (2002-2007) | 4.6 |