List of FDA approved drugs later pulled from market in the United States until 2014

Selected FDA-approved prescription drugs later recalled from the U.S. market until 2014 (in years)

The data illustrates a list of selected FDA-approved prescription drugs, which were later pulled from the United States market. The longest running FDA-approved drug which was later recalled from the market was Darvon & Darvocet, between 1955 and 2010, which stayed in the market for 55 years. The reason for the recall was serious toxicity to the heart: between 1981 and 1999 there were over 2,110 deaths reported connected to that drug. According to the Food and Drug Adminitration (FDA), a "drug is removed from the market when its risks outweigh its benefits.

Accutane, isotretinoin (1982-2009) 27
Baycol, cerivastatin (1998-2001) 3
Bextra, valdecoxib (2001-2005) 3.3
Cylert, pemoline (1975-2010) 30
Darvon & Darvocet, propoxyphene (1955-2010) 55
DBI, phenformin (1959-1978) 19
DES, diethylstibestrol (1940-1971) 31
Duract, bromfenac (1997-1998) 1
Ergamisol, levamisole (1989-2000) 11
Hismanal, astemizole (1988-1999) 11
Lotronex, astemizole (2000) 0.8
Meridia, sibutramine (1997-2010) 13
Merital & Alival, nomifensine (1982-1985) 3
Micturin, terodiline (1989-1991) 2
Mylotarg, gemtuzumab ozogamicin (2000-2010) 10
Omniflox, temafloxacin (1992) 0.3
Palladone, hydromorphone hydrochloride, extended-release (2005) 0.5
Permax, pergolide (1988-2007) 19
Pondimin, fenfluramine (1973-1997) 24
Posicor, mibefradil (1997-1998) 1
Propulsid, cisapride (1993-2000) 7
PTZ & Metrazol, pentylenetetrazol (1934-1982) 48
Quaaluude, methaqualone (1962-1985) 23
Raplon, rapacuronium (1999-2001) 2
Raptiva, efalizumab (2003-2009) 6
Raxar, grepafloxacin (1997-1999) 2
Redux, dexfenfluramine (1996-1997) 1
Rezulin, troglitazone (1997-2000) 3.25
Selacryn, tienilic acid (1979-1982) 3
Seldane, terfenadine (1985-1998) 13
Trasylol, aprotinin (1993-2008) 15
Vioxx, rofecoxib (1999-2004) 5.3
Xigris, drotrecogin alfa (2001-2011) 10
Zelmid, zimelidine (1982) 0
Zelnorm, tegaserod maleate (2002-2007) 4.6